Buy ADB FUBINACA | 100% good quality

$230

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Description

ADB FUBINACA

ADB FUBINACA is a designer drug identified in synthetic cannabis blends in Japan in 2013.[1] In 2018, it was the third-most common synthetic cannabinoid identified in drugs seized by the Drug Enforcement Administration.[2]

The (S)-enantiomer of ADB FUBINACA is described in a 2009 Pfizer patent[3] and has been reported to be a potent agonist of the CB1 receptor and the CB2 receptor with EC50 values of 1.2 nM and 3.5 nM, respectively.[3][4] ADB FUBINACA features a carboxamide group at the 3-indazole position, like SDB-001 and STS-135. ADB-FUBINACA appears to be the product of rational drug design, since it differs from AB-FUBINACA only by the replacement of the isopropyl group with a tert-butyl group.

An analogue of ADB-FUBINACA, ADSB-FUB-187, containing a more functionalized carboxamide substituent was recently reported.

adb fubinaca Side effects[edit]

One death through coronary arterial thrombosis has been linked to ADB FUBINACA intoxication.[5]

At least an additional 8 deaths in Hungary in 2015 are linked to the usage of this material, all deaths were youngsters below 21.

Metabolism[edit]

Twenty-three ADB FUBINACA major metabolites were identified in several incubations with cryopreserved human hepatocytes. Major metabolic pathways were alkyl and indazole hydroxylation, terminal amide hydrolysis, subsequent glucuronide conjugations, and dehydrogenation.[6]

Legality[edit]

In the United States, ADB FUBINACA is a Schedule I controlled substance.[7]

See also[edit]

References[edit]

  1. ^ Uchiyama N, Matsuda S, Kawamura M, Kikura-Hanajiri R, Goda Y (July 2013). “Two new-type cannabimimetic quinolinyl carboxylates, QUPIC and QUCHIC, two new cannabimimetic carboxamide derivatives, ADB-FUBINACA and ADBICA, and five synthetic cannabinoids detected with a thiophene derivative α-PVT and an opioid receptor agonist AH-7921 identified in illegal products”. Forensic Toxicology31 (2): 223–240. doi:10.1007/s11419-013-0182-9S2CID 1279637.
  2. ^ “Emerging Threat Report: Annual 2018” (PDF). Special Testing and Research Laboratory, Drug Enforcement Administration.
  3. Jump up to:a b WO 2009106982, “Indazole Derivatives”
  4. ^ Banister SD, Moir M, Stuart J, Kevin RC, Wood KE, Longworth M, et al. (September 2015). “Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, and 5F-ADBICA”. ACS Chemical Neuroscience6 (9): 1546–59. doi:10.1021/acschemneuro.5b00112PMID 26134475.
  5. ^ Shanks KG, Clark W, Behonick G (April 2016). “Death Associated With the Use of the Synthetic Cannabinoid ADB-FUBINACA”Journal of Analytical Toxicology40 (3): 236–9. doi:10.1093/jat/bkv142PMC 4885918PMID 26755539.
  6. ^ Carlier J, Diao X, Wohlfarth A, Scheidweiler K, Huestis MA (July 2017). “In Vitro Metabolite Profiling of ADB-FUBINACA, A New Synthetic Cannabinoid”Current Neuropharmacology15 (5): 682–691. doi:10.2174/1570159X15666161108123419PMC 5771045PMID 29403341.
  7. ^ “Schedules of Controlled Substances: Temporary Placement of Six Synthetic Cannabinoids (5F-ADB, 5F-AMB, 5F-APINACA, ADB-FUBINACA, MDMB-CHMICA and MDMB-FUBINACA) Into Schedule I”Drug Enforcement Administration.

ADB-FUBINACA is a new research chemical with similar effect to AB-FUBINACA. ADB-FUBINACA is a synthetic cannabinoid that has recently been identified in herbal blends. ADB-FUBINACA is a research chemical that acts as a potent agonist for the cannabinoid receptors which first was discovered in 2013 in Japan in a smoking mixture. ADB-FUBINACA appears to be the product of rational drug design, since it differs from AB-FUBINACA only by the replacement of the isopropyl group with a tert-butyl group. the IUPAC name is N-(1-Amino-3,3-dimethyl-1-oxo-2-butanyl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide, and the chemical formula is C21H23FN4O2, the purity of our ADB-FUBINACA is not less than 99.7%, strong quality, high purity and best price make our adb-fubinaca to be one of the most popular cannabiboids. ADB-FUBINACA is NOT intended for human or animal consumption, and just for research study only.

Properties of ADB FUBINACA

Name: ADB FUBINACA

CasNo: 1445583-51-6

IUPAC name: N-(1-Amino-3,3-dimethyl-1-oxo-2-butanyl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide

chemical formula: C21H23FN4O2

average mass: 382.431

monoisotopic mass: 382.180511

Appearance: white powder

Index of Refraction: 1.613

Molar Refractivity: 105.2±0.5 cm3

#H bond acceptors: 6

#H bond donors: 3

#Freely Rotating Bonds: 6

#Rule of 5 Violations: 0

Purity: 99.5%+

LimitNum: 10 Gram

Application: Pharmaceutical intermediates

DeliveryTime: within 24 hours

PackAge: packed in aluminum foil bag or as required.

Storage: Store in a cool dry place and keep away from direct strong light

Transportation: TNT, UPS, DHL, FEDEX, EMS and Client’s requests

Free samples can be available?

5g free ADB-FUBINACA sample can be offered to test quality, just pay shipping fee according to your destination.

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